Can Cannabidiol (CBD) Help Support Weight Loss and Metabolism?
Interestingly, over-activation of the endocannabinoid system, primarily via CB1 receptor activation,
contributes to increased abdominal obesity (i.e., fat gain along the midsection), glucose uptake
into adipocytes (fat cells), and insulin resistance in muscle tissue. This “metabolic dysfunction” sets up a
vicious cycle whereby further insulin resistance in muscles and the liver increases abdominal obesity and
further CB1 over-activation, resulting in greater food-seeking behavior, increased appetite, and increased body fat gain.